DNA's iconic double helix does more than "just" store genetic information. Under certain conditions it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed. The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a ...

The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible to the cellular machinery that works to express the right genes at the ...

Scientists have uncovered a surprising secret about our DNA: it’s not a static blueprint, but a constantly shifting, folding structure that helps control how genes turn on and off. Researchers at the ...

Before a cell can divide, it has to precisely duplicate its entire genetic information. However, the DNA in the cell exists as part of a DNA-protein complex known as chromatin. For this purpose, the ...

Every cell in your body faces the same engineering puzzle: how to cram roughly two meters of DNA into a nucleus just a few ...

The genome is more than a linear code; it is a dynamic structure whose three-dimensional folding dictates how genes are regulated. Traditional sequencing technologies capture base-level variation but ...

Estrogen is known as an important hormone, and it can control many cellular and bodily functions by regulating the activity of hundreds of genes. Scientists have now learned more about how estrogen ...

They were hardly modest, these two brash young scientists who in 1953 declared to patrons of the Eagle Pub in Cambridge, England, that they had "found the secret of life." But James Watson and Francis ...

The idea that modern humans inherited DNA from Neanderthal ancestors is one of the 21st century’s most celebrated discoveries ...